Business risk in pharmacuticual

Companies:
Johnson and Johnson 
Novartis AG
Pfizer
Merck & Co. 
Sanofi SA
Business Risks:
Top 5:
Intellectual Property
Information Security
Protection
Patents running out-sales 
Supply Chain reliance on third parties
Quality Control
Compliance
Patient Safety
i am doing the overview of the industry and analysis of business risks these is the companies we choose and the top 5 risks